Scientific Advisory Board

Paul J. Pockros, MD
Director, Scripps Clinic Research Consortium and Liver Disease Center
Dr. Pockros is a graduate of the University of Southern California (USC) School of Medicine and has been a member of Scripps Clinic since 1985. He is the past medical director of the Liver Transplantation Program at Scripps Clinic and has extensive experience in evaluating and caring for patients with serious liver conditions. As well, he is director of the Liver Disease Center at Scripps Clinic, one of the largest tertiary referral centers for chronic viral hepatitis in the United States. Dr. Pockros is a principal or co-investigator in a large number of clinical trials for treatments of chronic liver disease, especially for chronic viral hepatitis B and C. He is currently director of the Scripps Clinic Research Consortium, a group of 16 centers throughout the U.S. who participate in large multi-center liver disease trials. He lectures and is active in publication of journal articles in the areas of liver disease and particularly, new treatments for chronic viral hepatitis. He is chairman of the annual conference, "New Treatments in Chronic Liver Disease" held at Scripps Clinic each spring.
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Curt Scribner, MD, MBA
Sr.VP of Medical and Regulatory Affairs at RRD International
Dr. Scribner is a board certified physician in internal medicine and has direct experience running large clinical programs. Dr. Scribner joined RRD from Intarcia Therapeutics, where he was the Vice President of Regulatory and Quality Affairs and Chief Regulatory Officer. Previously, Dr. Scribner was Chief Regulatory Consultant for Quintiles Consulting where he developed and wrote numerous NDA, BLA, IND, IDE, 510(k), PMA and MAA applications. Prior to Quintiles Consulting, Dr. Scribner spent ten years at the Food and Drug Administration (FDA) where he held a variety of positions, and was involved in reviewing products regulated by the Center for Biologics. Dr. Scribner holds an MD from the University of Colorado College of Medicine, an MBA from the University of Maryland College of Business and Management.
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Katherine High, MD
William H. Bennett Professor of Pediatrics, Children's Hospital of Philadelphia; HHMI Investigator, University of Pennsylvania School of Medicine
Dr. High is a graduate of Harvard, the University of Pennsylvania, and the University of North Carolina School of Medicine. Dr High's special area of interest is in the series of enzymatic reactions that causes blood to clot. However, her research interests extend to several areas, including the molecular basis for hemophilia and thrombosis, or abnormal blood clotting. Her current research on a gene therapy approach to hemophilia hopes to lead to a therapeutic correction of blood Factor IX deficiency, allowing for the prevention of bleeds rather than their treatment after occurrence. Dr High is a Past President of the American Society for Gene Therapy (ASGT), a member of the FDA Cellular, Tissue and Gene Therapies Advisory Committee (CTGTAC) and the NHLBI Advisory Committee. She is also an Elected Councillor for the American Society of Hematology (ASH) and a member of Executive Committee. Dr. High remains an active and prominent clinical investigator using AAV.
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